Medicine and science in sports and exercise. Effect of creatine and weight training on muscle creatine and performance in vegetarians.

Journal of the International Society of Sports Nutrition. International Society of Sports Nutrition position stand: Safety and efficacy of creatine supplementation in exercise, sport, and medicine. Another study suggests that a cream containing creatine and folic acid improves sun damage and reduces wrinkles. Early research suggests that a cream containing creatine and other ingredients applied to the face every day for six weeks might reduce skin sag and wrinkles in men. There isn't enough evidence to recommend use of oral creatine as a heart failure treatment. Creatine supplementation might help counteract age-related declines in skeletal muscle and bone mineral density.

Creatine supplementation might improve performance during cognitive tasks, especially in older adults. In children with the certain creatine deficiency syndromes, oral creatine supplements might improve some symptoms.

Oral creatine might reduce the frequency of dehydration, muscle cramping, and injuries to the muscles, bones, ligaments, tendons and nerves.

Creatine is often used by athletes involved in high-intensity intermittent activities that require a rapid recovery during training and competition. Oral creatine use might allow an athlete to do more work during reps or sprints, leading to greater gains in strength, muscle mass and performance.

Strength, muscle size and performance.

Research on creatine use for specific activities and conditions shows:

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